
Profhilo Treatment London — Injectable Skin Hydration at Harley Street
Profhilo Treatment in London is an injectable skin bio-remodelling treatment designed to improve skin hydration, firmness and elasticity. At Dr Ophelia’s Harley Street clinic, Profhilo is used to treat skin laxity, crepiness and dehydration across the face, neck, hands and body, helping the skin look smoother, fresher and more radiant.
Profhilo contains a high concentration of hyaluronic acid, a substance naturally found in the skin. Unlike dermal fillers, Profhilo does not add volume or change facial shape. Instead, it spreads beneath the skin to deeply hydrate and stimulate collagen and elastin production, supporting firmer, healthier-looking skin over time.
What is Profhilo?
Profhilo is an injectable anti-ageing treatment made from stabilised hyaluronic acid. It is often described as a bio-remodelling treatment because it improves the quality of the skin rather than filling lines or adding structure.
Hyaluronic acid is naturally present in the skin and helps retain water, keeping the skin plump, smooth and hydrated. As we age, the body produces less hyaluronic acid, collagen and elastin. This can lead to dryness, reduced firmness, fine lines, crepey texture and visible skin laxity.
Profhilo is injected just beneath the skin using a precise technique. Once placed, it disperses quickly through the tissue, helping to hydrate the skin from within and stimulate the skin’s natural regenerative processes.
How Does Profhilo Work?
Profhilo works by delivering ultra-pure hyaluronic acid beneath the skin. The product spreads smoothly through the treated area, attracting water and improving hydration in the deeper layers of the skin.
In the first stage, many patients notice improved hydration and a fresher skin appearance. Over the following weeks, Profhilo gradually stimulates collagen and elastin production through the slow release of hyaluronic acid.
Collagen supports the skin’s structure and firmness, while elastin helps the skin remain flexible and resilient. By encouraging these processes, Profhilo can improve skin texture, tone, firmness and glow.
Profhilo is particularly useful for skin that looks tired, dehydrated, crepey or slightly loose. It can be used on the face, neck, hands, arms, stomach, knees and other areas where superficial tightening or hydration is needed.

Benefits of Profhilo Treatment
Profhilo is popular with patients who want natural skin rejuvenation without adding volume.
Potential benefits include:
- Improved skin hydration
- Firmer-looking skin
- Improved elasticity and bounce
- Smoother skin texture
- Softening of fine lines
- Healthier, more radiant skin
- Improvement in crepey or dehydrated skin
- Support for collagen and elastin production
- No facial volume change
- Minimal downtime
- Suitable for face, neck, hands and body areas
Profhilo can be used as a standalone treatment or as part of a wider skin rejuvenation plan alongside treatments such as skin boosters, anti wrinkle injections, dermal fillers or laser treatments.
Conditions Profhilo Can Treat
Profhilo may be suitable for a range of skin ageing and hydration concerns, including:
- Skin laxity
- Sagging skin
- Crepey skin
- Dehydrated skin
- Dull skin
- Fine lines and wrinkles
- Loss of elasticity
- Neck ageing
- Hand ageing
- Body skin laxity
Your consultation will determine whether Profhilo is the most suitable treatment for your concerns, or whether another injectable or skin treatment would be more appropriate.
What to Expect — Step-by-step process
Your Profhilo treatment begins with a consultation to assess your skin quality, areas of concern and treatment goals.
Dr Ophelia will assess your skin hydration, laxity, elasticity and overall skin quality. Your medical history and previous aesthetic treatments will also be reviewed.
A tailored plan is created based on the areas to be treated. Common areas include the face, neck, hands, arms, stomach and knees.
A topical anaesthetic cream may be applied before treatment to improve comfort.
Profhilo is injected just beneath the skin using a specially developed technique designed to reduce discomfort, downtime and the number of injection points required.
You will receive aftercare guidance, including advice on avoiding rubbing the area, intense exercise, heat exposure and certain skin treatments for a short period after your appointment.
The standard Profhilo protocol usually involves two sessions, spaced one month apart. In some cases, further sessions may be recommended if the skin is particularly dehydrated or affected by photo-ageing.
Follow-up treatments are usually recommended every 6–9 months to maintain results.

Results and Downtime
Profhilo has minimal downtime. Most patients can return to work and normal daily activities immediately after treatment.
Immediately after treatment
Small superficial bumps may be visible at the injection points. These are expected and usually settle within 24–48 hours as the product disperses.
24–48 hours
Any mild swelling, tenderness or injection marks should begin to settle. Bruising is possible, as with any injectable treatment.
4 weeks
Results typically begin to appear around four weeks after treatment. The skin may feel more hydrated, smoother and fresher.
8 weeks
After the second treatment, improvement in firmness, texture and glow usually becomes more noticeable as collagen and elastin stimulation develops.
6–12 months
Results typically last around 6–12 months, depending on your skin quality, age, lifestyle and maintenance plan. Follow-up treatments every 6–9 months can help maintain results.

Pricing / Number of Sessions
The recommended Profhilo protocol is usually two treatments, spaced four weeks apart. Some patients may benefit from a course of three treatments if the skin is very dehydrated, lax or affected by photo-ageing.
Current pricing:
Per treatment area, such as face or neck: £500
Course of 3 treatments: £1200
Three treatments spaced four weeks apart may be recommended for selected patients.
Pricing may vary depending on the area treated and the number of sessions recommended. Your personalised plan and full costs will be confirmed during consultation.
Why Dr Ophelia for Profhilo Treatment in London?
Profhilo is an injectable treatment that requires careful assessment, precise placement and a good understanding of skin ageing. At Dr Ophelia’s Harley Street clinic, treatment is delivered in a medically led setting with a focus on natural-looking rejuvenation.
Dr Ophelia Veraitch is an award-winning Consultant Dermatologist with expertise in skin health, ageing and personalised treatment planning. Rather than using a generic approach, she assesses your skin quality, hydration, laxity and overall goals before recommending the most appropriate treatment.
Patients choose Dr Ophelia for Profhilo Treatment in London because of her medical expertise, discreet Harley Street setting and subtle approach to injectable treatments. The aim is to improve your skin’s quality, firmness and glow while keeping your appearance natural.
HELP
FAQs
Profhilo contains hyaluronic acid like many dermal fillers, but it does not add volume or reshape the face. It acts as a hydrator and bio-remodeller, improving skin quality, firmness and elasticity.
Profhilo can be used on the face, neck, chest, hands, upper arms, stomach, knees and other areas where the skin is dehydrated, crepey or mildly lax.
The standard protocol is two treatments spaced one month apart. In some cases, three sessions may be recommended for dehydrated or photo-aged skin.
Results typically begin to appear around four weeks after treatment and continue to improve as collagen and elastin production is stimulated.
Results usually last around 6–12 months. Maintenance treatments every 6–9 months are often recommended to preserve results.
The procedure is quick and uses fine needles. Most patients tolerate it well, and topical anaesthetic can be applied before treatment to reduce discomfort.
Downtime is minimal. Small superficial bumps may appear at the injection sites and usually settle within 24–48 hours. Mild bruising or tenderness can occur.
Profhilo can help improve mild skin laxity, hydration and firmness. More significant sagging may require other treatments, which can be discussed during consultation.
Yes, Profhilo can be combined with treatments such as anti wrinkle injections, dermal fillers, skin boosters, laser treatments or microneedling as part of a wider rejuvenation plan.
Book Your Profhilo Consultation in London
If you are concerned about sagging skin, dehydration, crepiness, fine lines or loss of firmness, book a Profhilo consultation at Dr Ophelia’s Harley Street clinic in London. Your skin will be carefully assessed and a personalised treatment plan will be created to support smoother, firmer and more hydrated-looking skin.
Book your Profhilo consultation today and take the next step towards healthier, glowing skin.
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