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Profhilo Treatment London - Injectable Bio-Remodelling at Harley Street

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Profhilo Treatment London - Injectable Bio-Remodelling at Harley Street

Profhilo Treatment in London at Dr Ophelia's Harley Street clinic is a highly effective injectable skin bio-remodelling treatment that improves hydration, firmness, and elasticity across the face, neck, hands, and abdomen. As a Consultant Dermatologist, Dr Ophelia rarely uses it in isolation, combining it with prescription treatments, laser including Clear and Brilliant, PicoSure PRO and Fraxel, and other injectables such as anti wrinkle injections and polynucleotides, for skin rejuvenation beyond what a single injectable achieves.

Profhilo contains one of the highest concentrations of hyaluronic acid of any injectable available and works differently from a dermal filler: rather than adding volume, it spreads beneath the skin to hydrate and stimulate collagen and elastin, for skin that looks healthier, firmer, and more radiant, not treated.


What is Profhilo? 

  • One of the highest concentration hyaluronic acid injectables available 
  • Hydrates and bio-remodels, does not add volume or change facial shape 
  • Best results when combined with laser, injectables, and prescription skincare 
  • Suitable for face, neck, hands, and abdomen 

Profhilo is an injectable bio-remodelling treatment made from ultra-pure, stabilised hyaluronic acid. It is not a filler and does not add structure or volume; injected just beneath the skin, it hydrates from within and stimulates collagen and elastin over the weeks that follow. With age the skin makes less hyaluronic acid, collagen, and elastin, causing dryness and crepey texture; Profhilo works in the dermal layers topical products cannot reach.

How Does Profhilo Work? 

Profhilo delivers ultra-pure hyaluronic acid beneath the skin through a small number of precise injection points, and spreads through the tissue for a quick, visible improvement in skin quality. Over the following weeks the gradual release stimulates fibroblast activity, encouraging the skin to produce its own collagen and elastin, the bio-remodelling effect behind longer-term gains in firmness, elasticity, and texture.

Benefits of Profhilo Treatment 

Profhilo is a foundational skin quality treatment, most powerful within a broader dermatologist-led plan. 

Key benefits include: 

  • Deep hydration from within, at a level topical products cannot achieve 
  • Stimulation of collagen and elastin production through sustained hyaluronic acid release 
  • Improved skin firmness, elasticity, and bounce 
  • Smoother, healthier, more radiant looking skin 
  • Softening of fine surface lines and improvement in crepey texture 
  • Suitable for face, neck, hands, and abdomen 
  • No facial volume change or structural alteration 
  • Excellent combination treatment alongside anti wrinkle injections, polynucleotides, Clear and Brilliant, Fraxel, PicoSure PRO, and Thermage FLX 
  • Results further enhanced by prescription retinoids, growth factors, and antioxidant skincare available only through a Consultant Dermatologist 
  • Minimal downtime 
  • Two session standard protocol, with an optional third session for more dehydrated or photodamaged skin
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Conditions Profhilo Can Treat 

Profhilo may be suitable for a range of skin quality and ageing concerns, including: 

  • Skin laxity and mild sagging 
  • Crepey or dehydrated skin 
  • Dull, tired looking skin 
  • Fine lines and early wrinkles 
  • Loss of firmness and elasticity 
  • Neck ageing and skin crepiness 
  • Hand ageing and skin thinning 
  • Abdominal skin laxity, including post-pregnancy or post-weight-loss skin quality changes 
  • General improvement in skin quality and radiance as part of a preventative or maintenance plan 

Your consultation establishes which areas would benefit and what combination of treatments to use alongside Profhilo.

What to Expect - Step by Step Treatment Process 

Your treatment begins with a full skin assessment and consultation.

Results and Downtime

Immediately after treatment small superficial bumps may be visible at the injection points; these are expected and settle within 24 to 48 hours. 

24 to 48 hours Any mild swelling, tenderness, or injection marks settle, and bruising tends to be minimal. 

4 weeks results begin to appear, with skin feeling more hydrated and looking fresher, smoother, and more radiant; the second treatment is usually performed now. 

8 weeks After the second treatment, firmness, texture, and glow improve further as stimulation builds. 

6 to 12 months Results typically last around 6 to 12 months, depending on skin quality, age, and lifestyle, with supporting skincare and laser helping them keep improving; downtime is minimal and most patients return to normal activities immediately.

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Pricing and Number of Sessions 

The standard Profhilo protocol is two treatments, spaced four weeks apart. A third session is recommended for selected patients with more dehydrated or photodamaged skin. Maintenance treatments every six to nine months help sustain results. 

Current pricing: 

Face or neck: £500 per treatment Course of 3 treatments: £1,200 

Pricing for other areas including hands and abdomen will be confirmed at consultation. Where Profhilo is combined with other treatments as part of a broader plan, Dr Ophelia's team will provide clear, personalised pricing for the full programme before treatment begins.

Why Dr Ophelia for Profhilo Treatment in London? 

  • A Consultant Dermatologist who combines Profhilo with prescription skincare, laser, and injectables for superior results 
  • Access to prescription retinoids, growth factors, and antioxidants only available through a dermatologist 
  • Clear and Brilliant and Fraxel laser available in clinic to complement and extend Profhilo's effects 
  • Every injection performed personally by Dr Ophelia, with the full clinical context of a dermatologist-led skin plan 

Profhilo is one of the most effective injectable skin quality treatments available, but the result depends on the assessment, treatment plan, and skincare, managed differently by a Consultant Dermatologist than a standard aesthetic practitioner. Dr Ophelia can also prescribe pharmaceutical-grade retinoids, growth factor serums, and antioxidant formulations that maintain results between visits, for natural, dermatologist-led rejuvenation a single injectable cannot match.

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Frequently Asked Questions - Profhilo Treatment London

Book Your Profhilo Consultation in London 

If you are concerned about skin laxity, dehydration, crepiness, fine lines, or loss of firmness in the face, neck, hands, or abdomen, book a Profhilo consultation at Dr Ophelia's Harley Street clinic, where your skin is assessed in full and a personalised plan created. For injectable skin rejuvenation within a comprehensive, Consultant Dermatologist-led framework rather than a single appointment, this is where to come.

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